Paket Lengkap Uji Program Antidiabetes Dari Ekstrak Metanol Buah Kiwi (Actinidia Deliciosa) Melalui Penghambatan Program Α-Glukosidase

Abstract: Diabetes melitus (DM) is defined as a chronic metabolic disease or disorder with multiple etiologies characterized by high blood sugar levels. One way to treat diabetes mellitus is inhibiting the α-glucosidase enzyme. This study aims to determine the inhibition of α-glucosidase of methanol extract of kiwi fruit (Actinidia deliciosa) . Kiwi fruit (Actinidia deliciosa) contains saponins characterized by the formation of foam, positive flavonoid characterized by the formation of a yellow color (orange) and positive alkaloid which is characterized by brown color in wagner test. The inhibition activity test of α-glucosidase enzyme was performed by using spectrophotometric method. The results of the inhibition activity test of α-glucosidase enzyme in acarbose showed the value of 13,672 mg/L, while the methanol extract of kiwi fruit showed IC50 value of 7.219 mg/L. It demonstrated that the methanol extract of kiwi fruit has the inhibition activity greater than acarbose.

Keywords:Diabetes melitus, Phytochemicals, Kiwi fruit Actinidia deliciosa IC50.

Penulis: Okpri Meila, Noraini

Kode Jurnal: jpfarmasidd170578

Sumber https://fisikamilenial.blogspot.com/

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